Further Observations on GcMAF in Autism
January 19, 2012 16 Comments
My comments will follow this feedback on GcMAF for elevated nagalase from a mom.
Hi Dr Jeff,
6 days after first (GcMAF) injection I noticed the beginning of more intellectual observations and mature questions from him like: “What is hair made of?”… I say “cells”, he says, “What are cells?”… I say they are made of DNA from mom and dad, he says, “does that mean I have the same DNA as you and Rachel? (his sister)” …I say “yes”, he says, “so where did I come from before I was in your belly?” That’s where I choked and called my husband in to figure out what to say and also because I was so excited by all these great questions! :-)
This has been consistent throughout and after the 3rd injection which was last Saturday.
He does however appear to be having some more receptive language issues/auditory processing issues which cropped up recently which interestingly always seem to crop up when he is on an antiviral like valtrex (why we had to abandon that in the pas t— note: not prescribed by Dr Bradstreet). This appeared to coincide with the 3rd injection which was a little stronger.
He also has a mild epileptiform encephalopathy like LKS variant but hasn’t gotten IVIG in about 2 months. If this regulated calcium channels then potentially shouldn’t it IMPROVE subclinical seizure activity if it blocks calcium channels? Do you know if it regulates calcium channels to reduce hyperexcitability?
His originial nagalase was 1.9 about 3.5 weeks after ivig – I had heard ivig could possibly bind nagalase thus increasing blood levels so I’d be curious if kids on ivig have higher nagalase levels…
All in all though we’re pleased with his progress and I have heard it usually takes 4-5 weeks to even start seeing gains so we’re ahead of the curve!
This email I received is posted here with permission from the mother. I t brings up some interesting points and some things that need to be responded to.
1) There is no evidence or even reason to suspect IVIG alters nagalase transport or activity.
2) I have no evidence nagalase or GcMAF block calcium channels. Presumably and I cannot find much at all in the literature about this – GcMAF which acts as the blood transporter of Vitamin D plays a role in calcium channel function through the VDR-nuclear effects of Vitamin D. I do think some on my cases need less vitamin D and calcium on GcMAF but this observation is inconsistent. Abnormal regulation of calcium channels has been described in many disorder including certain types of epilepsy (absence) and chronic pain. Exactly how GcMAF and Vitamin D or VDR effect this remains unclear.
3 Early response to low dose GcMAF is very intriguing and it is hard to imagine it is due to viral elimination – more than likely it is related to other factors regulated through the Gc – Vitamin D – VDR – Vitamin D nuclear effects (DNA transcription) that regulate this type of response.
It remains a remarkable observation that minute doses of GcMAF have such a dramatic effect on children with ASD.